Unwanted side effects of sedating antihistamines One way no acc camsex free
Exposure to substances such as pollen, pet fur, peanuts, shellfish or insect bites can cause some people to produce an excess of a chemical called histamine.This causes allergic symptoms which can include swelling, skin rashes, sneezing, watery eyes, and a runny or blocked nose.This leads to significant central nervous system side effects, including sedation, drowsiness, somnolence, fatigue, cognitive decline, psychomotor effects, and loss of coordination.These antihistamines also are potent muscarinic receptor antagonists that can lead to serious anticholinergic side effects, such as sinus tachycardia, dry skin, dry mucous membranes, dilated pupils, constipation, ileus, urinary retention, and agitated delirium.3 The mnemonic “blind as a bat, dry as a bone, red as a beet, mad as a hatter, and hot as a hare” often is used to help describe and identify patients suffering from anticholinergic syndrome (see Table 2 below).It is used to relieve allergies (such as hay fever, food and drug allergies, and allergic skin reactions), and to relieve itching caused by infections such as chickenpox.It is also given to treat a type of allergic reaction called anaphylaxis, which is a medical emergency.H3 receptor antagonists could provide new treatment options for sleep disorders, weight loss, neuropathic pain, obesity, movement disorders, schizophrenia, attention deficit disorders, and Alzheimer’s dementia, while the development of antagonists for H4 receptors may lead to new treatment options for autoimmune inflammatory diseases.1,2 The first H1 sedating antihistamines have been available for more than 60 years and were synthesized based on a chemical structure similar to that used to develop cholinergic muscarinic antagonists, tranquilizers, and antihypertensive agents.
Chlorphenamine is available on prescription, or you can buy it without a prescription at pharmacies.
Older adults are especially sensitive to the central nervous system- and anticholinergic-related side effects of sedating antihistamines because of decreased cholinergic neurons or receptors in the brain, reduced hepatic and renal function, and increased blood-brain permeability.
These patients also often have coexisting conditions and often take multiple medications that increase the risk of drug-drug interactions and the potential for sedative adverse effects.
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them.
Children and people over 65 years of age may be more prone to side-effects from chlorphenamine.